Streamlining Variant Normalization on Large Genomic Datasets with Glow
Cross posted from the Glow blog. Many research and drug development projects in the genomics world involve large genomic variant data sets, the volume of which has been growing exponentially over the past decade. However, the tools to extract, transform, load (ETL) and analyze these data sets have not kept pace with this growth. Single-node...
Introducing Glow: an open-source toolkit for large-scale genomic analysis
The key to solving some of today’s most challenging medical problems lies in the analysis of genomics data. Understanding the impact of the minor changes in an individual’s genome on their overall health is fundamentally a data driven challenge that requires integration across hundreds of thousands of individuals. By analyzing genomes across large cohorts, researchers...